LIPITOR can be administered as a single dose at any time of the day, with or without food. Your doctor may occasionally change your dose to make sure you get the best results. In patients taking cyclosporine or the HIV protease inhibitor tipranavir plus ritonavir or the hepatitis C virus (HCV) protease inhibitor glecaprevir plus pibrentasvir or letermovir when co-administered with cyclosporine, therapy with LIPITOR should be avoided. The recommended starting dose of LIPITOR is 10 or 20 mg once daily. Atorvastatin belongs to a group of drugs called HMG CoA reductase inhibitors, or "statins.". Also call your doctor at once if you have: muscle weakness in your hips, shoulders, neck, and back. Follow your diet, medication, and exercise routines very closely. Zetia, simvastatin, fenofibrate, Lopid, rosuvastatin, Lipitor, Crestor, ezetimibe, pravastatin, evolocumab. Get emergency medical help if you have signs of an allergic reaction to atorvastatin: hives; difficulty breathing; swelling of your face, lips, tongue, or throat. Atorvastatin is used to treat high cholesterol, and to lower the risk of stroke, heart attack, or other heart complications in people with type 2 diabetes, coronary heart disease, or other risk factors. You may need to stop using this medicine for a short time if you have: an electrolyte imbalance (such as high or low potassium levels in your blood); It may take up to 2 weeks before your cholesterol levels improve, and you may need regular blood tests. The easiest way to lookup drug information, identify pills, check interactions and set up your own personal medication records. In patients taking clarithromycin, itraconazole, elbasvir plus grazoprevir, or in patients with HIV taking a combination of saquinavir plus ritonavir, darunavir plus ritonavir, fosamprenavir, fosamprenavir plus ritonavir or letermovir therapy with LIPITOR should be limited to 20 mg, and appropriate clinical assessment is recommended to ensure that the lowest dose necessary of LIPITOR is used. How long does atorvastatin stay in the system after stopping the drug? Children 10 to 17 years of age—At first, 10 mg once a day. The recommended starting dose of LIPITOR is 10 or 20 mg once daily. Avoid eating foods that are high in fat or cholesterol. LIPITOR may be used with bile acid resins. This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. Grapefruit and grapefruit juice may interact with atorvastatin and lead to potentially dangerous effects. Atorvastatin dosage information (in more detail). Drugs.com provides accurate and independent information on more than 24,000 prescription drugs, over-the-counter medicines and natural products. Renal disease does not affect the plasma concentrations nor LDL-C reduction of LIPITOR; thus, dosage adjustment in patients with renal dysfunction is not necessary [see Warnings and Precautions (5.1) and Clinical Pharmacology (12.3)]. Your doctor may increase your dose as needed. In patients taking clarithromycin, itraconazole, elbasvir plus grazoprevir, or in patients with HIV taking a combination of saquinavir plus ritonavir, darunavir plus ritonavir, fosamprenavir, fosamprenavir plus ritonavir or letermovir therapy with LIPITOR should be limited to 20 mg, and appropriate clinical assessment is recommended to ensure that the lowest dose necessary of LIPITOR is used. You may not notice any change in your symptoms, but keep using the medication as directed. Skip the missed dose if your next dose is less than 12 hours away. The starting dose and maintenance doses of LIPITOR should be individualized according to patient characteristics such as goal of therapy and response. You should not take atorvastatin if you are pregnant or breastfeeding, or if you have liver disease. Generic Name: atorvastatin (a TOR va sta tin) In rare cases, atorvastatin can cause a condition that results in the breakdown of skeletal muscle tissue, potentially leading to kidney failure. Available for Android and iOS devices. Generic name: ATORVASTATIN CALCIUM TRIHYDRATE 10mgDosage form: tablet, film coated. Version: 21.01. The easiest way to lookup drug information, identify pills, check interactions and set up your own personal medication records. Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use atorvastatin only for the indication prescribed. Serious drug interactions can occur when certain medicines are used together with atorvastatin. Last updated on Oct 7, 2020. Do not breastfeed while you are taking this medicine. Some patients may need to start at 40 mg per day. The recommended starting dose of LIPITOR is 10 mg/day; the usual dose range is 10 to 20 mg orally once daily [see Clinical Studies (14.6)]. Do not take extra medicine to make up the missed dose. Your blood work will help your doctor determine how long to treat you with atorvastatin. Avoid drinking more than 1 liter per day of grapefruit juice while taking this medicine. Tell each of your healthcare providers about all medicines you use now, and any medicine you start or stop using. Atorvastatin side effects (in more detail). LIPITOR should be used as an adjunct to other lipid-lowering treatments (e.g., LDL apheresis) in these patients or if such treatments are unavailable. Tell your doctor about all your current medicines and any you start or stop using, especially: This list is not complete. trouble lifting your arms, trouble climbing or standing; liver problems - upper stomach pain, weakness, tired feeling, loss of appetite, dark urine, jaundice (yellowing of the skin or eyes); or. Atorvastatin may pass into breast milk and could harm a nursing baby. kidney problems - little or no urinating, swelling in your feet or ankles, feeling tired or short of breath. Store at room temperature away from moisture, heat, and light. Follow your doctor's instructions very closely. Patients who require a large reduction in LDL-C (more than 45%) may be started at 40 mg once daily. You may report side effects to FDA at 1-800-FDA-1088. Select one or more newsletters to continue. Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. Take the medicine at the same time each day. Use effective birth control to prevent pregnancy while you are taking this medicine. -Atorvastatin dose should not exceed 20 mg/day when coadministered with clarithromycin, itraconazole, saquinavir plus ritonavir (use lowest dose necessary), darunavir plus ritonavir, fosamprenavir, fosamprenavir plus ritonavir, elbasvir plus grazoprevir, letermovir When co-prescribing atorvastatin with other protease inhibitors, appropriate clinical assessment is recommended to ensure that the lowest dose necessary of LIPITOR is used [see Warnings and Precautions (5.1) and Drug Interactions (7)]. For oral dosage form (tablets): For high cholesterol: Adults—At first, 10 or 20 milligrams (mg) once a day. The combination of HMG-CoA reductase inhibitors (statins) and fibrates should generally be used with caution [see Warnings and Precautions (5.1) and Drug Interactions (7)]. You should not use atorvastatin if you are allergic to it, or if you have: Atorvastatin can harm an unborn baby or cause birth defects. Certain other drugs can increase your risk of serious muscle problems, and it is very important that your doctor knows if you are using any of them. Is Repatha (evolocumab) effective without a statin. Data sources include IBM Watson Micromedex (updated 2 Nov 2020), Cerner Multum™ (updated 2 Nov 2020), ASHP (updated 23 Oct 2020) and others.